Year: 2016 | Month: February | Volume 6 | Issue 1
Cytotoxic and Anticancer Activity of F. Racemosa Fruit Extract on MCF7 Human Breast Cancer Cell Line by SRB Method
Abstract:
Present study was aimed to investigate the in vitro cytotoxicity and anticancer activity of F. racemosa on MCF7 human breast cancer cell line. Effect of ethanolic extracts of tender fruits of F. racemosa on MCF7 human breast cancer cell lines by Sulphorodamine B (SRB) assay was carried out. Three observations viz. LC50, TGI, GI 50 were recorded. The absorbance was recorded on an Elisa plate reader at a wavelength of 540 nm with 690 nm. F. racemosa showed LC50, TGI and GI50 activity at ≥ 80 μg/ ml concentration. Thus, it can be concluded that F. racemosa fruit extract hassome cytotoxic and anticancer activity (in vitro)at ≥ 80 μg/ ml concentration of plant extract on MCF7 human breast cancer cell line.
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